The following is an answer and/or comment by inhahe aka ColorStorm (inhahe.com - myriachromat.wordpress.com).
I think so. I think the main defining factors of our personalities are (in random order): 1. the personalities of our parents, and 2. who we already were before we were even conceived.

The first influence is a factor of nature, in the sense that I mean it. The second one is arguably beyond nature *and* nurture, depending, of course, on what you think of when you think of "nature" specifically in that question.

Probably the third-most defining factor, which is one of nurture, is the personalities/beliefs/values/attitudes/mannerisms of our culture and more particularly our local peers and the people we befriend. The aspects of personality that those things determine are a little more superficial than the aspects that factors #2 and maybe #1 determine, which are more about the core personality and the parts of you that makes you unique.

(There are mass/cultural trends and in personality and of course factors that are embedded in the common human genome, but there's also a lot of individual variation or uniqueness. (Though even the individual uniqueness tends to fall into a number of types/archetypes or roles.. depending on the person. Some people are more unique than others.))

Overall, I think what shapes our personalities most is whom we chose to be long before we were born (perhaps it's a personality that's shaped just like how we change and define ourselves in one individual life, but just over a much longer time-span and probably among different worlds), whether you want to call that nature or something else. That core personality doesn't typically change much over a person's lifetime.

On the other hand, when we think of one's personality, we're thinking mostly of the aspects of it that differentiate them from other humans and thus stand above the "base-line". In other words, there could be more to personality that *all* humans have in common that are based in the human form--and thus are based in biology and genetics--than what isn't, yet we just don't notice that, in much the same way we can't feel lukewarm water or don't feel the overwhelming 14-pounds-per-square-inch pressure exerted on us by our atmosphere.

I say the personality given to us by the human form is based in biology and hence genetics, but it's actually not that simple. The human form is actually a beautiful and ingenious representation of profound truths of the cosmos and the soul, even if it *is* genetically defined. This is why the human form is so beautiful to us, not because we're evolutionary-psychologically programmed to think it is, contrary to the academic and scientistic viewpoint of many (though evolutionary psychology probably does play a role in it, particularly where sexual attraction comes in).

So, even if it's still determined in some sense by genetics, the genetic composition itself could be considered, to some degree, an expression of spirit and hence ultimately expression of personality. (This is probably not only the case on the most universal level, but also on the individual level--I believe that there's some kind of correspondence that goes on between to-be-conceived spirit and the genetic make-up of the body, by whatever means.. there are a number of different possibilities.)

One of the reasons I believe that most of our core personality is shaped before birth is that it's *uncanny* how quickly a child's personality develops, gives how vividly unique it is unto themselves, like it just comes out of *nowhere*. There's not possibly enough time for the average child to creatively develop such identities or characters on their own, especially given their limited psychological sophistication and average levels of the capacity for creativity, and nor is there anyone around them that they're exposed to that has similar personality traits or energies. It's all from thin air, seemingly.